Physiological sciences chair named UF Research Professor

Dr. Paul Cooke

Dr. Paul Cooke

Dr. Paul Cooke, a professor and chair of the UF College of Veterinary Medicine’s department of physiological sciences, has received a UF Research Foundation professorship.

Sponsored by the university’s Office of Research, the professorships are awarded to tenured faculty members campuswide for distinguished research. The honor includes a $5,000 salary increase for three years, and a one-time $3,000 award for research support.

Cooke’s laboratory works in several areas of male and female reproductive biology. His current major research interest is in the role of membrane estrogen receptor 1, or ESR1, in male and female reproductive biology.

“Although descriptions of these membrane estrogen receptors go back to the 1960s and 1970s, there has been a long debate about exactly what they did, how they acted, and indeed whether or not they were important for estrogen action,” Cooke said.

His laboratory has recently been working with a newly developed mouse that has normal amounts of ESR1 in the cell nucleus, but lacks membrane ESR1. By examining the effects of the loss of membrane ESR1 in male or female reproduction, it is possible to determine for the first time exactly what role membrane ESR1 plays in male and female reproduction, Cooke added.

“Surprisingly, males lacking membrane ESR1 were infertile and had extensive reproductive abnormalities,” Cooke said. “This work indicated that membrane ESR1, which many considered peripheral in estrogen signaling, was actually essential for normal estrogen responses and fertility in males.”

Cooke’s work in this area was published in the journal Endocrinology in 2016, and was chosen as one of the top 5 endocrinology discoveries of 2016 by a group of endocrinology journals.

Since joining UF’s faculty in 2011 following a national search for a new chair of the physiological sciences department, Cooke has continued a productive career in research in addition to his administrative duties.


Share this article with others:
  • E-mail this story to a friend!
  • Facebook
  • Digg
  • Twitter

May-June 2018

Horse Rescue

UF VETS rescues blind mare from sinkhole

A blind, pregnant mare was rescued from a sinkhole, thanks to the UF Veterinary Emergency Treatment Service.

Beneficiaries receiving hens in Jdaydet Artooz. The effect of the civil war on livestock and poultry production systems in Syria has been significant, as production has dropped by 50 percent, according to surveys conducted by UN FAO in the region. (Copyright FAO/Syria)

UF veterinarians share expertise remotely at Syrian poultry conference

Unable to travel to Syria, two UF faculty members found a way to share information about poultry diseases remotely with farmers from the war-torn country.

Students outside of a veterinary practice.

Unique program at UF hones veterinary students’ business acumen

A unique program at the UFCVM helps veterinary students hone their business skills.

Veterinary technician manager Suzanne Pareau receives her Quality Hero award during a ceremony at UF Health on April 16. (Photo courtesy of Linda Allen)

Hospital employee honored by UF Health for patient care, safety efforts

A UF Small Animal Hospital veterinary technician manager received a “Quality Hero” award for her efforts to advance patient safety.

2018 Distinguished Award winners

College names 2018 Distinguished Award Winners

Veterinary practitioners and educators were among those honored as 2018 Distinguished Award winners.

Phi Zeta Student Winners

Top CVM research highlighted at Phi Zeta Day

Research achievement in various categories was honored during this year’s Phi Zeta Day activities.

Dr. Paul Cooke

Physiological sciences chair named UF Research Professor

Dr. Paul Cooke has received a UF Research Foundation professorship.

Rico, a miniature horse treated successfully at UF for a limb deformity, has recuperated well from his injuries. (Photo courtesy of Shelby Lewis)

Miniature horse thriving after rare surgery at UF Large Animal Hospital

Thanks to rare surgery performed at UF’s Large Animal Hospital, a miniature horse named Rico has returned to his normal routines.

Dr. Alex Alvarez

Surgery resident honored by national group

Dr. Alex Alvarez received the American Association of Veterinary Clinicians’ 2018 Resident Award.

...also in this issue



Around the College